Cook the rotini pasta according to package instructions until al dente. Drain and set aside.
In a large skillet or saucepan, combine the cooked chicken, Ro-Tel tomatoes, chicken broth, garlic powder, onion powder, salt, and pepper. Stir well.
Add the cubed Velveeta cheese to the skillet, stirring occasionally until melted and creamy.
Incorporate the cooked rotini pasta into the cheese mixture, stirring gently to combine.
Allow the mixture to simmer on low heat for 5–7 minutes, stirring occasionally.
Serve hot, garnished with chopped fresh cilantro.